Text
Drugs in Pregnancy and Lactation : A Reference Guide to Fetal and Neonatal Risk
It is now generally accepted that the developing fetus may be adversely affected by exposure to drugs and environmental chemicals. The stage of development of the intrauterine host is a major determinant of the resultant effect as well as the nature and the concentrationof the drug or chemical agent. On a more positive side, fetal therapy (i.e., treatment of fetal disease in utero by administering the drug to the mother or directly to the fetus) has been recognized recently as a rational approach to treat fetal disease. <br> <br> Forty years ago, the thalidomide catastrophe (limb defects) occured when this drug was administered to pregnant women as an antianxiety and hypnotic agent during the 1st semester.
Tidak tersedia versi lain