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The influence of medication diary-book for parents of patients with Nephrotic Syndrome on remission status
Background : Pediatric nephrotic syndrome (NS) are universally treated according to defined protocols. Adherence to medication is a crucial part of patient care and indispensable for reaching clinical goals. The aim of the study was to identify whether the medication book intervention may improve outcome in patients with Nephrotic syndrome. Method: A randomized study was conducted with 47 pediatric patients with NS in a pediatric nephrology outpatient clinic or ward. However, 3 subjects were not included in the analysis. Both intervention and control groups received a parental education program and medication as indicated by the attending doctors. The intervention group received
a medication diary-book to remind parents and families to medication. The treatment outcome, proteinuria and MMAS-8 were assessed after 4 weeks. Result : The remission status between intervention (n=22) and control group (n=20) were not different (p=0.346). In term of medication adherence (MMAS-8) showed average of 7.04+0.15 and 7.25+1.6 (p=0.353). There were 22 subjects who were included in the intervention group, the average compliance filling was 83.22+0.80% in the remission group while in the proteinuric (unresponsive) was 80+2.04%. Conclusion: There was no significant difference on the use of medication diary-book in for parents of NS. However, the average compliance filling is slightly higher in remission status patients in intervention group.
Keyword: Nephrotic syndrome, medication diary-book book, remission status
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